This Article supports SDG 3 by providing the first comprehensive review of the global burden of hepatis B and C in people with tuberculosis, through a systematic review and meta-analysis including 127 studies. The review found a high prevalence of these infections in this patient population, showing the need for routine hepatitis testing at the point of diagnosis of tuberculosis.
This Article supports SDG 3 by analysing several cohorts of people with HIV/HCV co-infection across 6 high-income countries, and identifying that a substantial proportion had not commenced direct-acting antiviral treatment for HCV infection despite unrestricted access. Factors associated with commencement or lack thereof are explored; for example, people with indicators of low engagement with HIV care (eg, not on antiretroviral therapy) were more likely not to have commenced HCV direct-acting antiviral treatment)
This study was designed to explore the relationship between Alzheimer's disease (AD) rates and socioeconomic conditions in 120 countries.
Elsevier,
Nutrition Science, Marketing Nutrition, Health Claims, and Public Policy, 2023, pp 297-305
This chapter aligns with Goal 3: Good Health and Wellbeing and Goal 12: Responsible Consumption by making public policymakers and nutrition marketers aware of how food and nourishment are linked to environmental conditions, as well as how sustainable approaches in nutrition marketing enhance positive behavior and build healthy societies.
Drinking water and sanitation services in high-income countries typically bring widespread health and other benefits to their populations.
Growing evidence suggests that the gut microbiome plays a crucial role in Alzheimer's disease (AD) pathogenesis through the microbiota-gut-brain axis, with alterations in gut microbiome composition linked to increased intestinal permeability, blood-brain barrier impairment, and neuroinflammation, and that gut microbiome modulation may alleviate AD symptoms, serve as a preventive measure, and also address comorbidities like Type 2 Diabetes Mellitus (T2DM), with future research directions including fecal microbiota transplantation (FMT) and precision medicine.
This review discusses the link between isolation, loneliness, and Alzheimer's Disease, and underscores the necessity of understanding and addressing these risk factors to develop successful prevention and treatment approaches.
This paper applies stochastic process models (SPM) to study Alzheimer's disease (AD) using data on AD onset and longitudinal body mass index (BMI) trajectories, revealing that APOE e4 carriers are less resilient to deviations in BMI, with age-related declines in adaptive response and differences in allostatic load accumulation, thereby providing new insights into the connections between age, genetic factors, and risk factors in AD development and aging.
This article investigates the potential therapeutic effects of glutamic-oxaloacetic transaminase (GOT) in Alzheimer's disease (AD) by reducing glutamate concentrations in the hippocampi of mice, leading to improved neurological function, reduced β-amyloid protein levels, enhanced cognitive performance, increased neuron count and synaptic density, and altered protein expression, suggesting a promising treatment approach for early-stage AD.
This review explores the potential therapeutic applications of the orexin system, focusing on its role as a target for treating various pathological conditions, including psychiatric and neurodegenerative diseases, and highlights the development of suvorexant as an orexin agent approved for insomnia treatment.
