Articles

The article describes the development of a self-regulated multi-functional nano-modulator (siR/PIO@RP) that can intelligently navigate to the damaged blood-brain barrier and release therapeutic cargoes for synergetic Alzheimer's disease (AD) therapy. The nano-modulator is capable of reducing cerebral amyloid-β load, relieving neuroinflammation, and alleviating the dysfunction of the neurovascular unit, providing proof of concept that normalizing the neurovascular unit holds promise as a means of alleviating AD symptoms.

This article describes how to make variables exogenous within International Futures integrated model to understand how forecasts created by others may interact with a broader set of outcome indicators like Shared Socioeconomic Pathways (SSPs).

The article concludes that the Mediterranean diet (MD) stands out as a model for sustainable and healthy eating, offering significant benefits for both human and planetary health. While it does not outperform vegetarian or vegan diets in terms of environmental impact, its nutritional quality, cultural acceptance, and moderate environmental footprint make it a practical and valuable dietary pattern. To maximize its benefits, policy and educational efforts should promote MD adherence and integrate sustainability considerations into dietary recommendations, addressing the challenges posed by globalization and shifting food preferences. Standardizing environmental impact measurements and considering broader sustainability indicators remain important areas for future research.

This text ties into SDG 13 (Climate Action) by focusing on innovative methods for CO2 capture using ionic liquids, which can help mitigate greenhouse gas emissions. It also relates to SDG 9 (Industry, Innovation, and Infrastructure) through the use of advanced computational approaches and generative models to accelerate the discovery and optimization of new materials.